Two names are already being discussed as potential challengers to incumbent senator Claire McCaskill, according to an Associated Press report. In 2006, McCaskill, a Democrat, beat then-incumbent and Republican Jim Talent by about 50,000 votes.
There's a chance Talent might try to win back his seat, according to the report.
"I am seriously considering it," he said in the report. "I do feel like this is a time where everybody has to think about what they can do to help the country. This is an obvious possibility for me. I have done it before, and I think I could put on a strong race."
Former state Treasurer Sarah Steelman is also deciding whether to run. According to the article, she faced a similar situation in 2009. She debated entering the Republican primary for retiring Senator Kit Bond's seat.
Several other people could run as well, including a former state party chairwoman Ann Wagner, according to the report.
Who would you like to see run for the seat?