Republicans were poised to increase their majority in the General Assembly by at least 19 seats.
Blaine Luetkemeyer's campaign stressed the need to create jobs and balance the federal budget.
Mayor Bob McDavid and his predecessor, Darwin Hindman, praised voters for passing an extension of the one-eighth-cent sales tax that pays for improvements to the city's parks.
There were a few bright spots for Democrats in the face of an anti-incumbent groundswell sweeping the nation, including key gubernatorial victories in New York, Massachusetts and Maryland.
Voters began turning out early Tuesday morning in Columbia and around Boone County. Polls opened at 6 a.m. and remained open until 7 p.m.
Republicans have seized control of the House for the first time since 2006, riding a wave of voter discontent and economic woes to directly challenge President Barack Obama's agenda.
Democrats lost Senate seats in at least five states Tuesday, but were guaranteed to keep the majority thanks to wins in California and West Virginia. Republicans scored big wins, taking Senate seats in Pennsylvania, Wisconsin, Arkansas, North Dakota and Indiana.
Data on how the Missouri elections stack up in the race for control of the U.S. Senate and House of Representatives.
Stephen Webber, the incumbent 23rd District representative, said he wants to continue the work he started in his first term. Challenger Paul Szopa said unemployment is the district's most important issue.
No immediate impact is expected from Amendment 1.
Though Missouri does not currently impose transfer taxes, Amendment 3 would prohibit any future taxes on real estate transactions from being implemented.
St. Louis and Kansas City currently levy 1 percent taxes on income and business revenues and, if passed, the proposition would subject those taxes to a vote in 2011 and every five years thereafter.
Mid-size and neighborhood park improvements is on the list of projects promised to be completed if city voters approve Proposition 1.
From President Bill Clinton is scheduled to be a special guest at Rep. Ike Skelton's fundraising dinner in New York.
Republican incumbent Blaine Luetkemeyer, Libertarian Christopher Dwyer and write-in Democrat Jeff Reed are running for positions in the U.S. House of Representatives.
While Blaine Luetkemeyer has raised a little more than $1.1 million for his campaign for U.S. Congress, his opponents, Christopher Dwyer and Jeff Reed, are using their modest finances to run grass-roots campaigns.
Missouri Secretary of State Robin Carnahan and U.S. Congressman Roy Blunt neglected the issues in a forum Friday by bickering at each other instead.
The Environment and Energy Commission is developing the ordinance, intended to create an incentive for landlords to make their properties more energy-efficient.
The study did not account for some important population groups in its numbers, so the outcome is not certain.
Candidates for both positions voiced their concerns of the county budget and economic issues before the Nov. 2 election.