Light snow, mixed at times with freezing drizzle, was expected to develop overnight and continue into Thursday morning, with accumulations of up to an inch of snow and a light glazing of ice, according to the National Weather Service.
Temperatures are expected to rise on Wednesday but still leave most of the United States below freezing.
While Columbia starts to warm up in the coming week, plumbers remind residents to remain wary of frozen pipes
Clearing roads was a challenge because it was so cold that salt was less effective, and the wind was whipping the fine, powdery snow back onto the cleared pavement.
Snow began to taper off by mid-afternoon, with accumulation between 7-9 inches. Wind gusts could create snow drifts and make travel hazardous. Temperatures were not expected to rise above zero on Monday.
By the pre-dawn hours of Monday, temperatures across much of Missouri will be below zero, perhaps as low as minus 10 with a wind chill of minus 25.
Roads in the Midwest were particularly dangerous. Missouri officials warned that it was too cold for rock salt to be effective. Schools were called off Monday for the entire state of Minnesota.
Experts offer tips on how to stay healthy and keep cars and homes working properly in extreme cold.
Columbia will see 4 inches of snow Saturday night, forecasters say. But temperatures will be relatively mild, the National Weather Service says, with a high of 40 and a low of 13.
The Public Works Department said Columbia's main roads are now "passable" after two to three inches of snow fell Wednesday night.
Several slide-offs occurred, but Capt. Tim Hull of the Missouri State Highway Patrol said there were no reports of fatalities.
The city's Public Works Department is asking residents to remove vehicles from priority snow routes. About 3 inches of snow is expected to accumulate between Wednesday afternoon and 5 a.m. Thursday.
Although Columbia will see the coldest temperatures of the year at the beginning of the week, the weather on Christmas Day should be warmer.
Freezing rain blanketed Columbia in ice, but streets stayed mostly clear on Saturday and Sunday, and the city avoided any snow accumulation.
Freezing rain covered much of Columbia in ice, but roadways were clear for much of Saturday. The threat that water on the roadways would freeze overnight could pose a risk to drivers, though.
The National Weather Service issued a winter storm warning that will be in effect through Sunday morning. Columbia residents can expect freezing rain, snow and poor driving conditions.
Priority roads in Columbia remained clear Sunday morning after crews spent Saturday plowing and treating roads.
Snow began falling in Columbia at 6 a.m. Sunday. Only 0.2 inches accumulated, but the icy conditions caused accidents on the highway, especially on bridges.
A fresh round of freezing rain and snow caused numerous accidents across slick roads in Missouri and Kansas on Sunday.
Travelers going to south could face cancelled flights and bad road conditions as a massive storms continues to travel east bringing rain, sleet and snow.