The extreme temperatures are expected to last all week.
An excessive heat warning for parts of Missouri and Illinois, including Columbia, will be in effect until late Thursday.
The Jackson County medical examiner was investigating the latest suspected heat death. No details have been released on any of the victims.
Columbia is under an excessive heat warning, according to the National Weather Service.
A heat advisory was issued for Columbia for Tuesday and Wednesday.
The oil well cap will stay closed despite evacuations from the Deepwater Horizon site during a tropical storm.
Strong thunderstorms brought heavy rain and flash flooding to parts of Missouri, Illinois and Iowa on Tuesday. The worst damage appears to be in Hannibal.
The heat index could reach 105 to 110 degrees this week in western and southwest Missouri.
The scorching hot temperatures: You're feeling it, and everybody's talking about it.
You can learn about air quality, pollutant levels and the UV index from the Environmental Protection Agency.
The heat index could get to 107 on Wednesday, according to the National Weather Service. Here is a list of places to stay cool if you do not have air conditioning.
In a matter of days, heavy rains have caused flooding and spread debris around Columbia. City crews were out cleaning fallen trees and loose dirt until 10 p.m. Wednesday.
Scattered storms are expected to produce up to 0.5 inches of rainfall, according to the National Weather Service.
The Missouri River was falling Monday from peak levels of last week, but moderate flooding continued in the northwest corner of the state.
A severe thunderstorm watch has been issued for northern Boone County.
Additional flooding in the already rain-soaked northwest Missouri could occur during an Army Corp of Engineers' water release out of a reservoir.
On Thursday, the Department of Natural Resources closed the campground at Lewis and Clark State Park until further notice because of flooding.
Holt saw an estimated 12 inches of rain in 42 minutes on the evening of June 22, 1947.
The National Weather Service Storm Prediction Center issued the watch at 2:45 p.m. It covers 45 counties from Boone County north to the Iowa line and west through Kansas City.
People dealt with Tuesday's sweltering temperatures with cool drinks, cooler water and cacti.