Accumulating snow, sleet and ice are predicted on Friday night, Saturday morning and again Tuesday. Strong winds and low humidity could risk fires along Interstate 70 on Thursday afternoon.
Actual temperatures will range from the teens in northern Kentucky to double-digits below zero in Minnesota, but even colder wind chills were expected.
On a rare warm January afternoon, the Columbia Disc Golf Club hosted its Ice Bowl Charity Tournament. Players aren't opposed to playing in poor conditions, which will likely arrive this week.
A high of 13 was forecast for Thursday with a low around 3 degrees Thursday night and wind chill values as low as minus 10.
A series of strong cold fronts moving east out of northern and northwestern Canada will keep temperatures low for the rest of the week.
Columbia reached a high of 50 degrees on Monday, just a week after a polar vortex brought negative temperatures to the area.
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Columbia residents were drawn outside by the sunny weekend weather, playing music, enjoying ice cream and making artwork downtown.
Light snow, mixed at times with freezing drizzle, was expected to develop overnight and continue into Thursday morning, with accumulations of up to an inch of snow and a light glazing of ice, according to the National Weather Service.
Temperatures are expected to rise on Wednesday but still leave most of the United States below freezing.
While Columbia starts to warm up in the coming week, plumbers remind residents to remain wary of frozen pipes
Clearing roads was a challenge because it was so cold that salt was less effective, and the wind was whipping the fine, powdery snow back onto the cleared pavement.
Snow began to taper off by mid-afternoon, with accumulation between 7-9 inches. Wind gusts could create snow drifts and make travel hazardous. Temperatures were not expected to rise above zero on Monday.
By the pre-dawn hours of Monday, temperatures across much of Missouri will be below zero, perhaps as low as minus 10 with a wind chill of minus 25.
Roads in the Midwest were particularly dangerous. Missouri officials warned that it was too cold for rock salt to be effective. Schools were called off Monday for the entire state of Minnesota.
Experts offer tips on how to stay healthy and keep cars and homes working properly in extreme cold.
Columbia will see 4 inches of snow Saturday night, forecasters say. But temperatures will be relatively mild, the National Weather Service says, with a high of 40 and a low of 13.
The Public Works Department said Columbia's main roads are now "passable" after two to three inches of snow fell Wednesday night.
Several slide-offs occurred, but Capt. Tim Hull of the Missouri State Highway Patrol said there were no reports of fatalities.