A three-run ninth spoiled rookie starter Michael Wacha's almost spotless showing in a soggy 4-2 loss to the Kansas City Royals on Thursday night.
Hall of Famer George Brett was named the club's interim hitting coach Thursday.
St. Louis goes for a sweep of Kansas City on Thursday with touted rookie Michael Wacha making his major league debut.
St. Louis improved to a major league-best 20-9 on the road before heading home for two gamesagainst Kansas City at Busch Stadium.
Michael Wacha, St. Louis' first-round pick last season, will playin his first major league game this week.
Under new coach Andy Reid, Kansas City has been showing progress while busily getting ready for the season as its players acclimate to one another and prepare for next week's mandatory minicamp.
Yadier Molina hit a home run and drove in four runs to help the St. Louis beat Kansas City 6-3 on Monday.
The Dodgers snapped the Cardinals' three-game winning streak with a 5-3 victory Saturday in Los Angeles.
The slumping Royals have lost 15 of 19, including seven straight at home. They have scored three runs or fewer in 12 of those defeats to drop a season-low four games below .500 at 21-25.
Micah Richards scored in extra time to cap a four-goal comeback for Manchester City in a 4-3 victory over rival Chelsea on Thursday night in the opener of a two-city U.S. tour.
Ervin Santana struck out eight, but he also gave up four home runs and Kansas City lost to the Los Angeles Angels 5-4 on Thursday night.
Tyler Lyons pitched seven solid innings on the same day St. Louis lost Jaime Garcia for the season, and the Cardinals beat the San Diego Padres 5-3 on Wednesday night.
The Cardinals anticipate attendance of about 46,000 for Thursday night's soccer match between Chelsea and Manchester, the first of two U.S. friendlies between the teams.
Daniel Descalso hit his first career grand slam, and Adam Wainwright (6-3) held the Padres to one run and four hits in 7 1/3 innings in the Cardinals' 10-2 victory Tuesday night at San Diego.
Royals starter James Shields pitched seven solid innings, but Kansas City managed just six hits in a 3-1 loss Wednesday night to the Houston Astros.
The Royals trailed and couldn't get much going offensively until the seventh when they cut the lead to one. Then a four-run eighth inning put them ahead for good in a 7-3 at Houston.
New Kansas City coach Andy Reid ran a version of the West Coast offense for years in Philadelphia, and the assumption is it will serve as the foundation for everything else. But already, the Chiefs are stacking plenty of wrinkles on top of it.
St. Louis rookie right-hander Shelby Miller saw his streak of 14 2/3 innings end in a 4-2 loss Monday at San Diego.
On Monday, the location changed but the result was the same when the Houston Astros got a 6-5 win over Kansas City.
Typically steady Lance Lynn had his second non-quality start of the season, lasting just five innings while giving up four earned runs on eight hits and two walks in St. Louis' 6-4 loss to Milwaukee on Saturday.