Cori Bush, a onetime homeless woman who led protests following a white police officer’s fatal shooting of a Black 18-year-old in Ferguson, ousted longtime Rep. William Lacy Clay Tuesday in Missouri’s Democratic primary, ending a political dynasty that has spanned more than a half-century.

Bush’s victory came in a rematch of 2018, when she failed to capitalize on a national Democratic wave that favored political newcomers such as Bush’s friend, Rep. Alexandria Ocasio-Cortez.

But this time around, Bush’s supporters said protests over the death of George Floyd in police custody in Minneapolis and outrage over racial injustice finally pushed her over the edge.

"This moment has really galvanized voters, especially in Missouri’s 1st" Congressional District, Bush campaign spokesman Keenan Korth said. "They’re ready to turn the page on decades of failed leadership."

Bush, 44, also had backing from political action committee Justice Democrats and Fight Corporate Monopolies this election. She campaigned for Vermont Sen. Bernie Sanders during his campaign.

Bush’s primary win essentially guarantees her a seat in Congress representing the heavily Democratic St. Louis area. Missouri’s 1st Congressional District has been represented by Clay or his father for a half-century. Bill Clay served 32 years before retiring in 2000. William Lacy Clay, 64, was elected that year.

Clay didn’t face a serious challenger until Bush. This year, he ran on his decades-long record in Congress.

Both Clay and Bush are Black, and Black residents slightly outnumber whites in the district that includes St. Louis and north St. Louis County.

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