The Spartans lost for the first time since Jan. 27, as the Kewpies surged ahead in the second quarter and held on for the victory.
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The Tigers were outscored in the third quarter for the ninth time in 12 SEC games this season, nullifying a strong effort in the fourth.
Hayley Frank is one of the nation's most effective free throw shooters, but her freshman season hasn't come without adjustments.
Elsewhere, the Rock Bridge and Tolton girls basketball teams both suffered losses Thursday night.
After a vibrant first half, Missouri women's basketball could not maintain its success as LSU charged ahead.
Missouri women's basketball nearly pulled off its best win of the year, but the No. 25 Razorbacks secured a comeback victory.
The Tigers will seek to avenge their Jan. 12 loss to the Razorbacks in a late Sunday afternoon contest at Mizzou Arena.
Elsewhere, Rock Bridge and Battle's wrestling squads competed at the Thrasher Invitational in St. Charles.
Kentucky men's coach John Calipari may have had a hand in spurring Kentucky women's basketball to a win over Missouri on Thursday.
Missouri women's basketball lost 72-53 at Texas A&M on Sunday, failing to capitalize on the injury to the Aggies' star.